Leeds Teaching Hospitals NHS Trust

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Haematological Malignancy Diagnostic Service, St. James' University Hospital
St. James' University Hospital LS9 7TF , United Kingdom

Accreditation

Active UKAS 9305
+44 (0)1132067963
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Accreditation Details

Accreditation Body

UKAS

Number

9305

Status

Active

Accreditation is granted under EU Regulation 765/2008 and assessed against ISO/IEC 17025. Data sourced from official UKAS records.

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Leeds Teaching Hospitals NHS Trust Leeds

Test Capabilities (178)
Standard Reference Description Category
CD4 CD4 Food Safety Testing
EBV EBV Food Safety Testing
Blood film - cell typing and morphology, manual White Blood Cell Blood film - cell typing and morphology, manual White Blood Cell Hematology
Bone Marrow | CD300e Bone Marrow | CD300e Hematology
CD34 CD34 Hematology
Differential for enumeration of cell types Differential for enumeration of cell types Hematology
Haematology examinations for the purpose of haematological malignancy diagnosis Haematology examinations for the purpose of haematological malignancy diagnosis Hematology
Leucocytes Leucocytes: | 8 Colours Hematology
Red Blood Cells Red Blood Cells Hematology
Activated B & T-cells, Reed Sternberg / Hodgkin’s cells Activated B & T-cells, Reed Sternberg / Hodgkin’s cells Histopathology / Cytology
Activated B-cells, plasma cells Activated B-cells, plasma cells Histopathology / Cytology
Activated T-cells, inter-leukin-2 receptor cells Activated T-cells, inter-leukin-2 receptor cells Histopathology / Cytology
Alk + tumours (ALCL) Alk + tumours (ALCL) Histopathology / Cytology
Assist in identification of positive cells in myeloid sarcomas and T-ALL Assist in identification of positive cells in myeloid sarcomas and T-ALL Histopathology / Cytology
B Cells B-Cells Histopathology / Cytology
B Cells | CD79a B-Cells | CD79a Histopathology / Cytology
B-cells & associated B-Cell lymphomas B-cells & associated B-Cell lymphomas Histopathology / Cytology
B-cells & associated B-Cell lymphomas, normal plasma cells B-cells & associated B-Cell lymphomas, normal plasma cells Histopathology / Cytology
B-cells, associated B-cell lymphomas B-cells, associated B-cell lymphomas Histopathology / Cytology
Broad spectrum of normal & neoplastic epithelia Broad spectrum of normal & neoplastic epithelia Histopathology / Cytology
Cells showing Myc translocation, disease related Cells showing Myc translocation, disease related Histopathology / Cytology
Cytotoxic T-cells & NK cells & related lymphomas Cytotoxic T-cells & NK cells & related lymphomas Histopathology / Cytology
Early T-cells & NK cells, related T-cell lymphomas Early T-cells & NK cells, related T-cell lymphomas Histopathology / Cytology
Embryonic cells & germ cells & related diseases Embryonic cells & germ cells & related diseases Histopathology / Cytology
Endothelial cells, Megakaryocytes Endothelial cells, Megakaryocytes Histopathology / Cytology
Endothelial cells, blast cells Endothelial cells, blast cells Histopathology / Cytology
Epithelial cells, Mantle cell lymphoma Epithelial cells, Mantle cell lymphoma Histopathology / Cytology
Erythroid cells & precursors Erythroid cells & precursors Histopathology / Cytology
Ewings sarcoma, lymphocytes Ewings sarcoma, lymphocytes Histopathology / Cytology
Follicular Helper T-cells Follicular helper T cells Histopathology / Cytology
Follicular dendritic cells, B-cells, CLL cells Follicular dendritic cells, B-cells, CLL cells Histopathology / Cytology
Follicular helper T-cells, angioblastic Follicular helper T-cells, angioblastic Histopathology / Cytology
Germinal centre B cells & related lymphomas Germinal centre B-cells & related lymphomas Histopathology / Cytology
Histiocytes Histiocytes Histopathology / Cytology
IDENTIFICATION OF: Antigens and antibodies in various auto-immune skin diseases Identification of: | Using culture media, latex Histopathology / Cytology
Identification of myeloid sarcomas and T-ALL Identification of myeloid sarcomas and T-ALL Histopathology / Cytology
IgA expressing plasma cells IgA expressing plasma cells Histopathology / Cytology
IgD expressing plasma cells, Mantle zone B-cells IgD expressing plasma cells, Mantle zone B-cells Histopathology / Cytology
IgG expressing plasma cells & lymphocytes IgG expressing plasma cells & lymphocytes Histopathology / Cytology
Kappa light chain expressing plasma cells and lymphoid cells (mantle zone B-cells) Kappa light chain expressing plasma cells and lymphoid cells (mantle zone B-cells) Histopathology / Cytology
Karposi sarcoma virus, associated multicentric Castleman’s disease Karposi sarcoma virus, associated multicentric Castleman’s disease Histopathology / Cytology
Lambda light chain expressing plasma cells and lymphoid cells (mantle zone B-cells) Lambda light chain expressing plasma cells and lymphoid cells (mantle zone B-cells) Histopathology / Cytology
Langerhan’s cells, IRDC’s Langerhan’s cells, IRDC’s Histopathology / Cytology
Macrophages & myeloid cells Macrophages & myeloid cells Histopathology / Cytology
Macrophages, monocytes Macrophages, monocytes Histopathology / Cytology
Mast cells, related disorders Mast cells, related disorders Histopathology / Cytology
Mature suppressor / cytotoxic T-cells, associated T-cell lymphomas Mature suppressor / cytotoxic T-cells, associated T-cell lymphomas Histopathology / Cytology
Megakaryocytes, megakaryocytes precursors, and platelets Megakaryocytes, megakaryocytes precursors, and platelets Histopathology / Cytology
Melanoma cells Melanoma cells Histopathology / Cytology
Morphological Assessment and Interpretation/Diagnosis Morphological assessment and interpretation/diagnosis Histopathology / Cytology
Myeloid Cells Myeloid cells Histopathology / Cytology
NK cells, nerve cells, neuroblastomas, some neoplastic PCs NK cells, nerve cells, neuroblastomas, some neoplastic PCs Histopathology / Cytology
NK cells, related lymphomas NK cells, related lymphomas Histopathology / Cytology
Neural cells, melanocytes Neural cells, melanocytes Histopathology / Cytology
Neural cells, neuroblastoma cells Neural cells, neuroblastoma cells Histopathology / Cytology
Normal & neoplastic epithelial cells (instestinal) Normal & neoplastic epithelial cells (instestinal) Histopathology / Cytology
Normal & neoplastic epithelia (breast) Normal & neoplastic epithelia (breast) Histopathology / Cytology
Normal & neoplastic epithelia (colon) Normal & neoplastic epithelia (colon) Histopathology / Cytology
Normal & neoplastic plasma cells, epithelial cells Normal & neoplastic plasma cells, epithelial cells Histopathology / Cytology
Pan Leucocyte marker- normal & neoplastic cells Pan Leucocyte marker- normal & neoplastic cells Histopathology / Cytology
Pan T-cell marker & T-cell lymphomas Pan T-cell marker & T-cell lymphomas Histopathology / Cytology
Plasma cells, activated T-cells, some germinal centre B-cells, R/S cells & associated lymphomas Plasma cells, activated T-cells, some germinal centre B-cells, R/S cells & associated lymphomas Histopathology / Cytology
Plasma cells, plasmacytic lymphoma vs myeloma Plasma cells, plasmacytic lymphoma vs myeloma Histopathology / Cytology
Proliferating Cells Proliferating Cells Histopathology / Cytology
Prostate glandular tissue, related carcinomas Prostate glandular tissue, related carcinomas Histopathology / Cytology
Reticulin Fibres Reticulin fibres Histopathology / Cytology
Rhabdomyosarcoma & Ewings tumour cells Rhabdomyosarcoma & Ewings tumour cells Histopathology / Cytology
Rhabdomyosarcoma cells Rhabdomyosarcoma cells Histopathology / Cytology
Smooth & striated muscle Smooth & striated muscle Histopathology / Cytology
Specific subtype of plasma cells, IgG4 disease Specific subtype of plasma cells, IgG4 disease Histopathology / Cytology
Suggestive of Hairy Cell Leukaemia Suggestive of Hairy Cell Leukaemia Histopathology / Cytology
T Cell Lymphomas T-cell lymphomas Histopathology / Cytology
T-cells, mantle zone B-cells, neoplastic B-cells ( CLL, MCL), T-cell lymphomas T-cells, mantle zone B-cells, neoplastic B-cells ( CLL, MCL), T-cell lymphomas Histopathology / Cytology
T-helper cells & related lymphoma T-helper cells & related lymphoma Histopathology / Cytology
Transcription factor, monocytic lineage, early granulocytes Transcription factor, monocytic lineage, early granulocytes Histopathology / Cytology
Tubercle Bacilli Tubercle bacilli Histopathology / Cytology
Amyloid Amyloid Immunology / Serology
B-ALL: TdT B-ALL: | 8 colours Immunology / Serology
B-cell screen (BLS): CD19 B-cell screen (BLS): | 8 colours Immunology / Serology
Bone Marrow | CD235a Bone Marrow | CD235a Immunology / Serology
CD10 CD10 Immunology / Serology
CD105 CD105 Immunology / Serology
CD117 CD117 Immunology / Serology
CD11b CD11b Immunology / Serology
CD13 CD13 Immunology / Serology
CD138 CD138 Immunology / Serology
CD14 CD14 Immunology / Serology
CD15 CD15 Immunology / Serology
CD16 CD16 Immunology / Serology
CD19 CD19 Immunology / Serology
CD1A CD1a Immunology / Serology
CD2 CD2 Immunology / Serology
CD20 CD20 Immunology / Serology
CD22 CD22 Immunology / Serology
CD25 CD25 Immunology / Serology
CD27 CD27 Immunology / Serology
CD3 CD3 Immunology / Serology
CD33 CD33 Immunology / Serology
CD36 CD36 Immunology / Serology
CD38 CD38 Immunology / Serology
CD44 CD44 Immunology / Serology
CD45 CD45 Immunology / Serology
CD5 CD5 Immunology / Serology
CD56 CD56 Immunology / Serology
CD57 CD57 Immunology / Serology
CD59 CD59 Immunology / Serology
CD64 CD64 Immunology / Serology
CD7 CD7 Immunology / Serology
CD71 CD71 Immunology / Serology
CD79b CD79b Immunology / Serology
CD8 CD8 Immunology / Serology
CD81 CD81 Immunology / Serology
KAPPA Kappa Immunology / Serology
LAMBDA Lambda Immunology / Serology
MPO MPO Immunology / Serology
Outreach monitoring (CMP): CD19 Outreach monitoring (CMP): | 6 colours Immunology / Serology
Plasma cell screen: CD38 Plasma cell screen: | 8 colours Immunology / Serology
Rituximab monitoring Rituximab monitoring: | 6 colours Immunology / Serology
Stem Cell Screen (SCS): CD64 Stem Cell Screen (SCS): | 8 colours Immunology / Serology
T-ALL T-ALL: | 6 colours Immunology / Serology
T-cell screen (TLS): CD3 T-cell screen (TLS): | 8 colours Immunology / Serology
Detection of fusion gene transcripts and determination of breakpoint regions [Definitive list HMDS-GOV-A&C-5] Detection of fusion gene transcripts and determination of breakpoint regions [Definitive list HMDS-GOV-A&C-5] Molecular Diagnostics / PCR
Detection of known SNVs and small indels [Definitive list HMDS-GOV-A&C-4] Detection of known SNVs and small indels [Definitive list HMDS-GOV-A&C-4] Molecular Diagnostics / PCR
Detection of nucleic acid sequence variants - SNVs and small indels [Definitive listHMDS-GOV-A&C-13 ] Detection of nucleic acid sequence variants - SNVs and small indels [Definitive listHMDS-GOV-A&C-13 ] Molecular Diagnostics / PCR
Determination of fragment length size and detection of deletions, known Determination of fragment length size and detection of deletions, known Molecular Diagnostics / PCR
Fragments sizing for detection of known SNVs [Definitive list HMDS-GOV-A&C-4] Fragments sizing for detection of known SNVs [Definitive list HMDS-GOV-A&C-4] Molecular Diagnostics / PCR
Genomics analysis for the purpose of clinical diagnosis, prognosis, and patient management Genomics analysis for the purpose of clinical diagnosis, prognosis, and patient management Molecular Diagnostics / PCR
HLA DR HLA-DR Molecular Diagnostics / PCR
Quantification of SNVs and small indels [Definitive list HMDS-GOV-A&C-5] Quantification of SNVs and small indels [Definitive list HMDS-GOV-A&C-5] Molecular Diagnostics / PCR
Quantification of breakpoint regions of fusion transcripts [Definitive list HMDS-GOV-A&C-5] Quantification of breakpoint regions of fusion transcripts [Definitive list HMDS-GOV-A&C-5] Molecular Diagnostics / PCR
Quantification of major breakpoint regions in BCR-ABL1 fusion transcripts [Definitive list: HMDS-GOV-A&C-5] Quantification of major breakpoint regions in BCR-ABL1 fusion transcripts [Definitive list: HMDS-GOV-A&C-5] Molecular Diagnostics / PCR
RNA extraction and preparation of cDNA, for subsequent in-house analysis (see below), referral to specialist centres and long term storage RNA extraction and preparation of cDNA, for subsequent in-house analysis (see below), referral to specialist centres and long term storage Molecular Diagnostics / PCR
SNVs and indels, gene rearrangements, internal tandem duplications and microsatellites [Definitive list HMDS-GOV-A&C-4] SNVs and indels, gene rearrangements, internal tandem duplications and microsatellites [Definitive list HMDS-GOV-A&C-4] Molecular Diagnostics / PCR
SNVs and small indels SNVs and small indels Molecular Diagnostics / PCR
Screening of large targeted single or multigene panels for genetic variants [Definitive list HMDS-GOV-A&C-8 Screening of large targeted single or multigene panels for genetic variants [Definitive list HMDS-GOV-A&C-8 Molecular Diagnostics / PCR
Screening of large targeted single or multigene panels for genetic variants [Definitive list HMDS-GOV-A&C-8] Screening of large targeted single or multigene panels for genetic variants [Definitive list HMDS-GOV-A&C-8] Molecular Diagnostics / PCR
B- & T- lymphoproliferative disorders B- & T- lymphoproliferative disorders Other
CD123 Human CD123 Other
CD157 CD157 Other
CD16/CD56 CD16/CD56 Other
CD24 CD24 Other
CD304 CD304 Other
CD305 (LAIR-1) CD305 (LAIR-1) Other
CD3d CD3d Other
CD45RA CD45RA (All B lymphocytes; | CD45RA Other
CD58 CD58 Other
CD61 CD61 Other
CD66c CD66c Other
CD73 CD73 Other
CD86 CD86 Other
CD9 CD9 Other
Chronic myeloid disorders - MDS/CML/CMML Chronic myeloid disorders - MDS/CML/CMML Other
Detection and analysis of genomic rearrangements and imbalances in: Haemato-Oncological disorders Bone Marrow failure Identification/confirmation of genomic rearrangements, gains and losses – using locus specific probes: Break apart Dual colour dual fusion Copy Number/Amplification ALK Breakapart IGH/MAFB [Definitive list of probes HMDS-GOV- A&C-3] Detection and analysis of genomic rearrangements and imbalances in: Haemato-Oncological disorders Bone Marrow failure Identification/confirmation of genomic rearrangements, gains and losses – using locus specific probes: Break apart Dual colour dual fusion Copy Number/Amplification ALK Breakapart IGH/MAFB [Definitive list of probes HMDS-GOV- A&C-3] Other
Detection of DNA copy number variation and loss of heterozygosity Detection of DNA copy number variation and loss of heterozygosity Other
Diagnosis of follicular lymphoma Diagnosis of follicular lymphoma Other
Differentiation of different haemopoietic cells Differentiation of different haemopoietic cells Other
Flaer Alexa-488 Flaer Alexa-488 Other
Identification of normal or aberrant Identification of normal or aberrant Other
Immunophenotyping of the following markers/antigens in an 8-colour panel to diagnose and monitor myeloid disorders (AML, MDS, CMML) Immunophenotyping of the following markers/antigens in an 8-colour panel to diagnose and monitor myeloid disorders (AML, MDS, CMML) Other
Immunophenotyping of the following markers/antigens to assess the deficiency of GPI linked antigens on red blood cells and leucocytes (PNH panel) Immunophenotyping of the following markers/antigens to assess the deficiency of GPI linked antigens on red blood cells and leucocytes (PNH panel) Other
Immunophenotyping of the following markers/antigens to diagnose and monitor Acute lymphoblastic leukaemia (B-ALL & T-ALL) Immunophenotyping of the following markers/antigens to diagnose and monitor Acute lymphoblastic leukaemia (B-ALL & T-ALL) Other
Immunophenotyping of the following markers/antigens to diagnose and monitor mature B- and T-cell lymphoproliferative disorders: Extended B-cell panel: CD19 CD20 CD23 CD43 CD81 CD79b CD5 ROR1 CD95 CD31 CD49d CD305 (LAIR-1) CD38 CD10 CD25 CD11c CD103 CD200 CD39 CD22 CD196 CD185 IgG IgD IgM CD27 Immunophenotyping of the following markers/antigens to diagnose and monitor mature B- and T-cell lymphoproliferative disorders: Extended B-cell panel: CD19 CD20 CD23 CD43 CD81 CD79b CD5 ROR1 CD95 CD31 CD49d CD305 (LAIR-1) CD38 CD10 CD25 CD11c CD103 CD200 CD39 CD22 CD196 CD185 IgG IgD IgM CD27 Other
Immunophenotyping of the following markers/antigens to screen for, diagnose or monitor: Acute leukaemia - AML/B-ALL/T-ALL Immunophenotyping of the following markers/antigens to screen for, diagnose or monitor: Acute leukaemia - AML/B-ALL/T-ALL Other
Kikuchi disease Kikuchi disease Other
Leukaemia cells Leukaemia cells Other
Mantle Cell Lymphoma Mantle Cell Lymphoma Other
Monocytes, macrophages, Hairy Cell Monocytes, macrophages, Hairy Cell Other
Morphological assessment of haematopoietic cells Morphological assessment of haematopoietic cells Other
Myeloid cells, Reed Sternberg cells Myeloid cells, Reed Sternberg cells Other
Myeloma/MGUS Myeloma/MGUS Other
NG2 NG2 Other
Normal T & B-lymphocyte precursors Normal T & B-lymphocyte precursors Other
PML protein expression pattern in suspected cases of Acute PML protein expression pattern in suspected cases of Acute Other
Promyelocytic Leukaemia Promyelocytic Leukaemia Other
T-ALL & B-ALL cells T-ALL & B-ALL cells Other
TCR  TCR  Other
TCR  TCR  Other
TDT TDT Other

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